Trace a Variant Report From HGVS to ClinVar

The alias problem A report contains an HGVS coding name, a gene symbol, and a database link. The team wants to know whether a ClinVar entry is the same variant. Comparing aliases without the reference sequence can create false matches. Traceability Name -> Reference -> Condition -> Review context HGVS standardizes how variants are described. ClinVar aggregates submitted interpretations. The safest trace keeps identity and interpretation context separate. loose alias BRCA mutation A reproducible lookup Identity first, interpretation second. 01 Name 02 Match 03 Try it Capture the name Step 1

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